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The data revealed that myricetin (orally twice a day, 100 mg/kg/day, for 6 moths) inhibited the IB/NF-B pathway, with this pathway being independent of nuclear factor erythroid 2-related factor (Nrf2) regulation

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These compounds work individually and together through several mechanisms of action, including stimulating the bodys metabolic master switch AMP-activated protein kinase (AMPK), an enzyme that acts to burn stored fat and inhibit the creation of new fat cells